Denver’s Gummies: Altitude AC Nuking Liver Enzymes?

By Franklin Everett Shaw

February 26, 2026

Ever wonder why that hike up Lookout Mountain felt way harder than it should have? Or why that “altitude adjustment” gummy you popped before hitting Red Rocks left you feeling…off? It might be more than just thin air. Denver’s unique altitude, combined with the ingredients in those seemingly harmless gummies, could be putting your liver under unexpected stress. Let’s dive into the potential link between altitude adjustment gummies, liver enzymes, and the Mile High City.

The problem isn’t necessarily the altitude itself, but how your body reacts to it. At 5,280 feet (and higher in many Denver neighborhoods), your body works harder to get the oxygen it needs. This increased effort can lead to physiological changes, including increased red blood cell production and altered metabolic processes. Now, throw in a gummy packed with herbs, vitamins, and other compounds, and you’ve got a complex cocktail interacting with your already stressed system.

Let’s talk about those gummies. Many “altitude adjustment” products contain ingredients like Rhodiola Rosea, Ginkgo Biloba, and B vitamins. While these are often touted for their potential to improve oxygen utilization and reduce altitude sickness symptoms, they can also have side effects, especially when combined with the physiological stress of altitude. For example, some studies suggest that high doses of certain B vitamins can, in rare cases, lead to elevated liver enzymes. Rhodiola Rosea, while generally considered safe, can interact with certain medications and may cause mild side effects in some individuals.

The real concern arises when these ingredients interact with the liver. The liver is your body’s primary detoxification organ, responsible for processing everything you ingest. When the liver is overworked, it can release enzymes like Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) into the bloodstream. Elevated ALT and AST levels are often indicators of liver damage or inflammation.

So, how do you know if your altitude adjustment gummies are affecting your liver? Pay attention to the symptoms. These can be subtle and easily dismissed as just part of the altitude adjustment process itself. Look out for:

• Fatigue that’s more pronounced than usual.
• Loss of appetite or nausea.
• Abdominal pain, especially in the upper right quadrant.
• Jaundice (yellowing of the skin and eyes) – a more severe symptom.
• Dark urine or light-colored stools.

If you experience any of these symptoms, especially after consuming altitude adjustment gummies, it’s crucial to consult with a healthcare professional. Don’t just brush it off as “altitude sickness.”

Getting your liver enzymes checked is a simple blood test. Your doctor will order a comprehensive metabolic panel (CMP), which includes ALT and AST levels. Normal ranges vary slightly between labs, but generally, ALT should be below 45 U/L and AST below 40 U/L. If your results are significantly elevated, further investigation may be needed to determine the underlying cause.

Now, let’s get practical. What can Denver residents do to mitigate the risk of elevated liver enzymes while acclimating to altitude?

1. Prioritize Gradual Acclimation: Don’t rush into strenuous activities immediately upon arrival. Give your body time to adjust to the lower oxygen levels. Spend a few days taking it easy, hydrating well, and avoiding overexertion.

2. Hydrate, Hydrate, Hydrate: Denver’s dry climate exacerbates the effects of altitude. Drink plenty of water to help your body function optimally and support liver function. Aim for at least half a gallon of water per day, and even more if you’re active.

3. Limit Alcohol Consumption: Alcohol puts extra stress on the liver. Reduce or eliminate alcohol intake, especially during the initial acclimation period.

4. Be Mindful of Supplements: Carefully evaluate the ingredients in altitude adjustment gummies and other supplements. Research potential side effects and interactions. Consider consulting with a doctor or registered dietitian before taking any new supplements, especially if you have pre-existing liver conditions.

5. Consider Alternative Acclimation Strategies: Instead of relying solely on gummies, explore other methods of altitude acclimation. These include:

   • Spending time at progressively higher altitudes: If possible, gradually increase your altitude over several days.
   • Using supplemental oxygen: For individuals with pre-existing respiratory conditions or those experiencing severe altitude sickness, supplemental oxygen can be beneficial.
   • Following a high-carbohydrate diet: Carbohydrates are a more efficient fuel source at altitude.

6. Choose Reputable Brands: If you do choose to use altitude adjustment gummies, opt for reputable brands that conduct third-party testing for purity and potency. This helps ensure that you’re getting what’s advertised and minimizing the risk of contaminants.

7. Listen to Your Body: Pay attention to how you feel. If you experience any adverse symptoms after taking altitude adjustment gummies, discontinue use and consult with a healthcare professional.

A common mistake is assuming that all altitude adjustment gummies are created equal. The reality is that the quality and composition of these products can vary significantly. Some may contain higher doses of certain ingredients than others, increasing the risk of side effects. Others may contain contaminants or adulterants that can further stress the liver.

Another pitfall is relying solely on gummies as a “magic bullet” for altitude acclimation. While they may provide some benefit, they are not a substitute for proper hydration, gradual acclimation, and other healthy lifestyle choices.

Denver residents need to be particularly vigilant about their liver health, especially when using altitude adjustment gummies. The combination of altitude-related physiological changes and the potential side effects of certain gummy ingredients can put the liver under extra stress. By being aware of the risks, recognizing the symptoms, and adopting proactive strategies, you can protect your liver health and enjoy all that the Mile High City has to offer. Don’t let a gummy ruin your Rocky Mountain experience.