**Santa Fe Guts: Is Altitude Crushing Enzyme Youth?**

Photograph of Franklin Everett ShawBy Franklin Everett Shaw
November 2, 2025

Have you ever felt like your digestion just isn’t what it used to be, especially after moving to Santa Fe? It’s not just the green chile; the altitude plays a significant role, particularly as we age.

Santa Fe, New Mexico, boasts an elevation of approximately 7,000 feet above sea level. This high altitude presents unique physiological challenges, especially for older adults, impacting everything from oxygen absorption to digestive enzyme production. Let’s dive into how this affects your gut and what you can do about it.

At higher altitudes, the body experiences lower oxygen levels, a condition known as hypoxia. This hypoxia triggers a cascade of physiological responses, including increased red blood cell production and altered metabolic processes. One often overlooked consequence is the impact on digestive enzyme production.

Digestive enzymes, such as amylase, protease, and lipase, are crucial for breaking down carbohydrates, proteins, and fats, respectively. These enzymes are primarily produced in the pancreas and small intestine. Studies have shown that hypoxia can impair pancreatic function, leading to reduced enzyme secretion. This is because the pancreas, like any other organ, requires sufficient oxygen to function optimally.

A study published in the Journal of Applied Physiology found that prolonged exposure to high altitude significantly decreased pancreatic enzyme activity in animal models. While human studies are limited, the underlying physiological principles suggest a similar effect in humans, particularly in older adults whose organ function may already be compromised.

Reduced enzyme production means that food isn’t broken down as efficiently. This can lead to a host of digestive issues, including:

  • Bloating
  • Gas
  • Abdominal discomfort
  • Indigestion
  • Nutrient malabsorption

Nutrient malabsorption is a particularly serious concern. If your body isn’t properly breaking down and absorbing nutrients, you could become deficient in essential vitamins and minerals, even if you’re eating a healthy diet. This can exacerbate age-related health issues and compromise overall well-being.

The gut microbiome, the complex community of microorganisms living in your digestive tract, is also affected by high altitude. Hypoxia can alter the composition and function of the gut microbiome, potentially leading to dysbiosis, an imbalance of beneficial and harmful bacteria.

Research suggests that high altitude can decrease the diversity of the gut microbiome and increase the abundance of certain bacteria associated with inflammation and gut permeability (leaky gut). This can further impair nutrient absorption and contribute to systemic inflammation.

A study conducted in the Tibetan Plateau, a region with extremely high altitude, revealed significant differences in the gut microbiome composition of residents compared to those living at lower altitudes. The high-altitude residents had a lower diversity of gut bacteria and a higher prevalence of bacteria associated with carbohydrate metabolism, likely due to dietary adaptations to the harsh environment.

So, what can Santa Fe residents, particularly older adults, do to mitigate these digestive challenges? Here are some actionable strategies:

  1. Supplement with Digestive Enzymes: Consider taking a broad-spectrum digestive enzyme supplement with each meal. Look for a product that contains amylase, protease, lipase, and cellulase to support the breakdown of various food components. Brands like NOW Foods and Garden of Life offer reputable digestive enzyme formulas readily available at local health food stores like La Montanita Co-op.

  2. Optimize Your Diet: Focus on easily digestible foods. Cooked vegetables are generally easier to digest than raw vegetables. Soups and stews, common in New Mexican cuisine, can be particularly beneficial. Incorporate fermented foods like sauerkraut or kimchi (if tolerated) to support a healthy gut microbiome.

  3. Prioritize Hydration: High altitude can lead to dehydration, which can further impair digestive function. Drink plenty of water throughout the day. Consider adding electrolytes to your water, especially after exercise or outdoor activities.

  4. Manage Stress: Stress can negatively impact digestion. Practice stress-reducing techniques such as meditation, yoga, or spending time in nature. Santa Fe offers numerous opportunities for outdoor recreation, which can be a great way to de-stress.

  5. Consider Probiotics: A high-quality probiotic supplement can help restore balance to your gut microbiome. Look for a probiotic that contains multiple strains of beneficial bacteria, such as Lactobacillus and Bifidobacterium. Consult with a healthcare professional to determine the best probiotic for your individual needs.

  6. Address Underlying Conditions: If you have any underlying digestive conditions, such as irritable bowel syndrome (IBS) or small intestinal bacterial overgrowth (SIBO), it’s crucial to address them with the help of a healthcare professional. These conditions can be exacerbated by high altitude.

  7. Be Mindful of Alcohol Consumption: Alcohol can irritate the digestive tract and impair nutrient absorption. Limit your alcohol intake, especially when first adjusting to the altitude.

  8. Incorporate Local, Gut-Friendly Foods: Take advantage of Santa Fe’s unique culinary offerings. Blue corn, a staple in New Mexican cuisine, is a good source of fiber, which can promote healthy digestion. However, be mindful of portion sizes, as excessive fiber can sometimes cause bloating.

  9. Gradual Acclimatization: If you’re new to Santa Fe, give your body time to adjust to the altitude. Avoid strenuous activities during the first few days and gradually increase your activity level as you acclimatize.

  10. Consult with a Healthcare Professional: If you’re experiencing persistent digestive issues, it’s essential to consult with a healthcare professional. They can help identify any underlying causes and recommend appropriate treatment options. A registered dietitian specializing in gut health can also provide personalized dietary recommendations.

One common pitfall is assuming that digestive issues are simply a normal part of aging. While digestive function may naturally decline with age, the high altitude in Santa Fe can exacerbate these issues. Don’t dismiss your symptoms; take proactive steps to support your digestive health.

Another mistake is relying solely on over-the-counter remedies without addressing the underlying causes. While antacids and other medications can provide temporary relief, they don’t address the root of the problem. Focus on making sustainable lifestyle changes to support long-term digestive health.

For example, Maria, a 70-year-old Santa Fe resident, had been experiencing persistent bloating and indigestion for several months. She initially attributed her symptoms to aging and tried various over-the-counter remedies with little success. After consulting with a registered dietitian, she learned about the impact of high altitude on digestive enzyme production. Maria started taking a digestive enzyme supplement with each meal and made dietary adjustments, such as incorporating more cooked vegetables and fermented foods. Within a few weeks, her symptoms significantly improved, and she was able to enjoy her meals without discomfort.

Living in Santa Fe offers a unique and vibrant lifestyle, but it’s essential to be aware of the potential health challenges associated with high altitude. By understanding how altitude affects digestive enzyme production and gut health, and by implementing the strategies outlined above, you can optimize your digestive function and enjoy a healthy and fulfilling life at 7,000 feet. Don’t let altitude hold you back from savoring the flavors and experiences that Santa Fe has to offer.

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