Taos Altitude: Is Thin Air Hiding Liver Lies?

Photograph of Franklin Everett ShawBy Franklin Everett Shaw
November 4, 2025

Imagine you’re standing on the porch of a cozy cabin in Taos, New Mexico, the crisp mountain air filling your lungs. You feel invigorated, alive. But what if that same air, that same altitude, is subtly altering your blood work, specifically your liver function tests? It’s a question many residents and visitors of Taos, perched at over 7,000 feet, should be asking.

The liver, a workhorse of an organ, is responsible for detoxification, metabolism, and a host of other vital functions. Liver function tests (LFTs) are a common way to assess its health, measuring enzymes and proteins in the blood. But in Taos, interpreting these tests requires a nuanced understanding of how altitude affects the human body.

So, does the thin air of Taos skew your LFTs? The answer, frustratingly, is “it’s complicated.” While direct, definitive research on altitude’s sole impact on LFTs is limited, we can extrapolate from related studies and physiological principles to paint a clearer picture.

One key factor is hypoxia, the reduced oxygen availability at high altitudes. The body responds by increasing red blood cell production to carry more oxygen. This process, called erythropoiesis, is stimulated by erythropoietin (EPO), a hormone primarily produced by the kidneys. However, the liver also plays a role in EPO production, and chronic hypoxia could theoretically influence liver function, albeit indirectly.

Another consideration is dehydration. The dry air at high altitude leads to increased fluid loss through respiration. Dehydration can concentrate blood components, potentially affecting LFT results. While not directly damaging the liver, it can create misleadingly elevated levels.

Let’s consider Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST), two common LFT markers. These enzymes are released into the bloodstream when liver cells are damaged. While altitude itself is unlikely to directly cause significant liver cell damage, strenuous physical activity at high altitude, combined with dehydration, could lead to a transient elevation in these enzymes. Think of a visitor from sea level going for a vigorous hike on the trails near Taos Ski Valley.

Alkaline Phosphatase (ALP) is another LFT marker. It’s found in the liver, bones, and other tissues. While less directly linked to altitude, conditions like bone stress fractures, which might be more common in active individuals at high altitude due to the increased physical demands, could elevate ALP levels.

Bilirubin, a waste product from the breakdown of red blood cells, is also measured in LFTs. While altitude doesn’t directly impact bilirubin metabolism, any condition that increases red blood cell turnover (like the aforementioned erythropoiesis) could theoretically influence bilirubin levels, though usually not significantly.

So, what’s a Taos resident or visitor to do? First, hydration is key. Drink plenty of water, especially when engaging in physical activity. Aim for clear urine throughout the day.

Second, acclimatize gradually. Don’t push yourself too hard physically in the first few days after arriving in Taos. Give your body time to adjust to the lower oxygen levels.

Third, be aware of potential confounding factors. Medications, alcohol consumption, and underlying medical conditions can all affect LFTs. Disclose all relevant information to your healthcare provider.

Fourth, consider altitude-adjusted ranges. While not universally adopted, some labs and physicians may use slightly adjusted reference ranges for LFTs in high-altitude areas. Discuss this with your doctor. A slight elevation within the “normal” range at sea level might be perfectly acceptable in Taos.

Fifth, repeat the test. If your LFTs are mildly elevated, your doctor may recommend repeating the test after a period of acclimatization and lifestyle modifications. This can help determine if the elevation is transient and related to altitude or if further investigation is needed.

Let’s imagine a hypothetical scenario: Maria, a 45-year-old woman from Dallas, Texas, visits Taos for a week-long art retreat. She enjoys hiking and exploring the area. Upon returning home, she has a routine physical, and her LFTs show a mild elevation in ALT and AST. Her doctor, unfamiliar with the potential effects of altitude, immediately suspects liver disease.

However, Maria remembers her strenuous hikes in Taos and the fact that she might not have been adequately hydrated. She informs her doctor about her trip and suggests repeating the LFTs after a few weeks. The repeat tests come back normal, confirming that the initial elevation was likely related to her high-altitude activities.

This scenario highlights the importance of communication and awareness. Healthcare providers, especially those outside of high-altitude regions, need to be educated about the potential influence of altitude on LFTs.

Now, let’s address some common pitfalls. One mistake is attributing all abnormal LFT results to altitude. While altitude can play a role, it’s crucial to rule out other potential causes of liver disease, such as viral hepatitis, alcohol abuse, non-alcoholic fatty liver disease (NAFLD), and autoimmune disorders.

Another pitfall is ignoring significantly elevated LFTs. A mild, transient elevation might be altitude-related, but markedly abnormal results warrant further investigation.

When should you seek further specialized evaluation? If your LFTs are significantly elevated, if you have other symptoms of liver disease (such as jaundice, abdominal pain, or fatigue), or if your LFTs remain abnormal despite acclimatization and lifestyle modifications, you should consult a gastroenterologist or hepatologist.

These specialists can perform additional tests, such as liver biopsies or imaging studies, to determine the underlying cause of your abnormal LFTs. They can also provide personalized recommendations for treatment and management.

Living in or visiting Taos, New Mexico, is a unique experience. The stunning scenery and vibrant culture are undeniable draws. However, it’s essential to be aware of the potential physiological effects of high altitude, including its possible influence on liver function tests. By understanding these effects and taking appropriate precautions, you can ensure that your liver health remains optimal, allowing you to fully enjoy all that Taos has to offer. Remember, knowledge is power, especially when it comes to your health in the high country.

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